Home Department: Human Biology
Mentor: Yanmin Yang, Neurology & Neurological Sciences
Neurons rely on a highly organized microtubule structure that controls essential cell functions. Although impairment of this microtubule network is a hallmark of several neurodegenerative diseases, including Alzheimer’s, we currently have a limited understanding of the molecular mechanisms by which microtubules are regulated. Brandon’s research seeks to further modern understanding of microtubule organization by characterizing the mechanism of action of Nemitin, a newly discovered microtubule organizing protein found in developing cells and in neurons. Identifying Nemitin’s mechanism of action will better allow for targeted therapies for neurodegeneration.