Home Department: Bioengineering
Mentor: Fan Yang, Orthopaedic Surgery and Bioengineering
Using micro-ribbon scaffolds, which promote robust stem cell-based bone formation, Omeed will develop physiologically-relevant 3D in vitro models to mimic breast cancer-bone metastasis. He will study the role of breast cancer cells in promoting the destruction of bone tissue and elucidate the effect of bone resorption on breast cancer growth and invasion. Omeed’s summer project is at the interface of cancer biology, biomaterials, tissue engineering and orthopaedic surgery and will provide novel 3D in vitro cancer models, a powerful tool for enabling discovery of novel molecular targets to treat breast cancer-bone metastasis with reduced materials, time, and cost.